[R] Simulation Case/Control R Beginner
Claire_6700
chriseverclear at hotmail.com
Tue May 6 23:37:29 CEST 2008
I am looking for a way to simulate genotypes of cases and control at a
disease locus in R. I am supposed to set the allele frequency as
control/cases. for each of the column below simulate 200 snp dataset.
I am looking at treesim function from popgen to stimulate the genotypes in
R.
Here is what i have
size case control
2000 0.6 0.15
2500 0.1 0.17
what am i missing in the treesim parameter and how do i calculate the
p-value of trend test?
I am a bit confused with the parameter.
N<-2000
Sn<-200
theta<-0
a<-treesim(N, Sn, theta, rho.vec, mutations=FALSE, sample=FALSE)
mat<-LDmat(.....)
Here is the documentation.
http://cran.r-project.org/web/packages/popgen/popgen.pdf
any help will really be helpful.
thank you,
Claire
--
View this message in context: http://www.nabble.com/Simulation-Case-Control-R-Beginner-tp17092885p17092885.html
Sent from the R help mailing list archive at Nabble.com.
More information about the R-help
mailing list