[R] Coefficients of Logistic Regression from bootstrap - how to get them?

Frank E Harrell Jr f.harrell at vanderbilt.edu
Thu Jul 24 20:35:09 CEST 2008

Michal Figurski wrote:
> Thank you all for your words of wisdom.
> I start getting into what you mean by bootstrap. Not surprisingly, it 
> seems to be something else than I do. The bootstrap is a tool, and I 
> would rather compare it to a hammer than to a gun. People say that 
> hammer is for driving nails. This situation is as if I planned to use it 
> to break rocks.
> The key point is that I don't really care about the bias or variance of 
> the mean in the model. These things are useful for statisticians; 
> regular people (like me, also a chemist) do not understand them and have 
> no use for them (well, now I somewhat understand). My goal is very 
> practical: I need an equation that can predict patient's outcome, based 
> on some data, with maximum reliability and accuracy.
> I have found from the mentioned paper (and from my own experience) that 
> re-sampling and running the regression on re-sampled dataset multiple 
> times does improve predictions. You have a proof of that in that paper, 
> page 1502, and to me it is rather a stunning proof: compare 56% to 82% 
> of correctly predicted values (correct means within 15% of original value).

Michal I think you are misinterpreting that paragraph, although it's 
hard to know exactly what they mean there.  I think it is a comparison 
of a naive stepwise regression approach to a more pre-specified approach 
that selects the model using a more unbiased criterion than that used by 
stepwise selection.  Resampling can be useful for selecting the form of 
the model in some cases.  But your original post dealt with resampling 
from a single pre-specified model which is not what the authors used.

(remainder omitted)


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