[R] one-site competition data // curve fitting

Gabor Grothendieck ggrothendieck at gmail.com
Tue Jul 8 14:47:21 CEST 2008


Check out the drc package.

On Mon, Jul 7, 2008 at 5:15 AM, Thiemo Schreiber
<schreibe at biochem.mpg.de> wrote:
> Hello everyone,
>
> I have biological data from a competition experiment where a free ligand is titrated against the binding of a protein.
>
> Now, I would like to fit a standard on-site binding curve to this data in order to obtain the IC50 and Kd values.
> Unfortunately I have not been able to find a package/function which allows such a fitting and calculates the results.
>
>
> Does anyone know if there is a suitable package available and which function to apply?
>
> Thanks a lot.
>
> Cheers
> Thiemo Schreiber
>        [[alternative HTML version deleted]]
>
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