[R] R equivalent of S+SeqTrial?

[Douglas Bates]

On 3/28/07, Marc Schwartz <marc_schwartz at comcast.net> wrote:
> On Wed, 2007-03-28 at 02:42 -0700, francogrex wrote:
> > Does anyone know of an R package that is equivalent of S+SeqTrial for
> > analysis of clinical trials using group sequential methods? Thanks.
>
> I don't know that there are fully functional equivalents, but you might
> want to look at the following:
>
> 1. The GroupSeq package on CRAN:
>
>   http://cran.r-project.org/src/contrib/Descriptions/GroupSeq.html
>
>
> 2. The ldBands() function in Frank Harrell's Hmisc package on CRAN:
>
>   http://biostat.mc.vanderbilt.edu/s/Hmisc/html/ldBands.html
>
> This also requires the ld98 executable, which is available from:
>
>   http://www.biostat.wisc.edu/landemets/

There is also the ldbounds package on CRAN for calculating Lan-DeMets
boundaries.  It was prepared by students working with Dave DeMets and
does not require the ld98 executable.