[R] M-value and fold change

[solie.alizadeh at utoronto.ca]

Hi everyone,

I have a question about M value and how it corresponds to gene  
expression fold change.I
was wondering if for example M-value of -1.27 which means 0.41 in fold  
change, doesn it
mean 0.41 of the control (in my experiment wild type? Better say does  
it mean this gene
is down-regulated by 41% or 59% (1-41)? I was abit confused about it.  
I appreciate if
anyone can help me to figure this out.

Thanks in Advance,
Solmaz Alizadeh