[R] exact 95% confidence intervals
Frank E Harrell Jr
f.harrell at vanderbilt.edu
Wed Sep 27 14:30:10 CEST 2006
Peter Dalgaard wrote:
> "XinMeng" <xmeng at capitalbio.com> writes:
>> Hello sir:
>> As to the 2*2 table format for reporting results comparing a new
>> test to true diagnosis,when I got the sensitivity and
>> specificity,how can I calculate the exact 95% confidence intervals
>> (based on the binomial distribution) for sensitivity and specificity
>> via R?
> Just run binom.test on the data from each column (or row, depending on
> which way you turn the tables).
But beware of exact binomial intervals - they are often not very
accurate. Wilson and other intervals are generally better. For example
see the binconf function in the Hmisc package.
Frank E Harrell Jr Professor and Chair School of Medicine
Department of Biostatistics Vanderbilt University
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