[R] Stats question - cox proportional hazards adjustments

Peter Dalgaard p.dalgaard at biostat.ku.dk
Wed Sep 20 14:47:00 CEST 2006


"Geoff Russell" <geoffrey.russell at gmail.com> writes:

> Hi useRs,
> 
> Many studies of the link between red meat and colorectal cancer use
> Cox proportional
> hazards with (among other things) a gender covariate.
> 
> If it is true that men eat more red meat, drink more alcohol and smoke more than
> women, and if it is also true that alcohol and tobacco are known risk
> factors then why does
> it make sense to "adjust" for gender?   I would think that in this
> case some of the
> risk that should be properly attributed to the bad habits will actually end
> up being attributed to being male instead.

This is more than a bit off-topic for the list, but in (very) brief:
Because you need to get rid of purely gender related effects that
disturb the analysis and may create spurious association.

Otherwise you would become able to "prove" effects like stiletto heels
causing breast cancer, etc. 

-- 
   O__  ---- Peter Dalgaard             Øster Farimagsgade 5, Entr.B
  c/ /'_ --- Dept. of Biostatistics     PO Box 2099, 1014 Cph. K
 (*) \(*) -- University of Copenhagen   Denmark          Ph:  (+45) 35327918
~~~~~~~~~~ - (p.dalgaard at biostat.ku.dk)                  FAX: (+45) 35327907



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