[R] Use of least-squares means, are they misleading?

[Felipe]

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Hi.
Sorry for sending this question twice, but I would really like to know
your opinion on this topic.

I have been reading about the (in)convenience of using least-squares
means (a. k. a. adjusted means) in multiple comparisons (I used to
resort to them when using SAS). I even read a post in this list warning
against them, but not giving much detail.

What is your opinion? Should I avoid using LSmeans for comparison (e.g.
after ANOVA)?

Greetings.

Felipe

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