[R] measurement error model - "simple" linear regression

[Andrew Robinson]

Dear Troels,

you might try McArdle, Limnol. Oceanogr., 48(3), 2003, 1363-1366 for
some reading, and the pls package (newly updated) for tools.

(I apologize if this information replicates previous postings, but
Googling R-help McArdle 2005 draws a blank so I think I'm on safe
ground!)

Good luck!

Andrew

On Sun, Oct 16, 2005 at 10:40:17PM +0200, Troels Ring wrote:
> Dear friends, I found the thread on this subject this summer but 
> wonder whether it has been taken any further. I have an important 
> medical problem where X is computed from a three independent and 
> complicated measurements (exchangeable sodium and potassium and total 
> body water - i.e. X = (Nae+Ke)/TBW ) and Y is serum sodium 
> concentration (all data in Edelman, JCI 1958). I have the individual 
> data in the paper (but have not yet had time to enter it) and Edelman 
> et al in fact reported measurement errors for most individual items. 
> Edelman and coworkers made a linear regression of Y on X and now I 
> would like to ascertain the importance of the fact that X was 
> measured with error for the utility of the formula in clinical 
> practice (since I believe it is being misused by ignoring this fact - 
> and more). I found in Neter, Wasserman and Kutner 3. ed a general 
> discussion of the problem - but would very much like a more recent 
> presentation if available and application in R.
> 
> Best wishes
> 
> Troels Ring
> Aalborg, Denmark
> 
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-- 
Andrew Robinson
Senior Lecturer in Statistics                       Tel: +61-3-8344-9763
Department of Mathematics and Statistics            Fax: +61-3-8344-4599
University of Melbourne, VIC 3010 Australia
Email: a.robinson at ms.unimelb.edu.au    Website: http://www.ms.unimelb.edu.au