[R] global normalization

Berton Gunter gunter.berton at gene.com
Thu May 26 00:40:13 CEST 2005

Please address this question to the appropriate BioConductor or other
microarray list (or to the limma package author, as the Posting Guide asks).
It is not appropriate for R-Help.

-- Bert Gunter
Genentech Non-Clinical Statistics
South San Francisco, CA
"The business of the statistician is to catalyze the scientific learning
process."  - George E. P. Box

> -----Original Message-----
> From: r-help-bounces at stat.math.ethz.ch 
> [mailto:r-help-bounces at stat.math.ethz.ch] On Behalf Of 
> Sent: Wednesday, May 25, 2005 3:33 PM
> To: r-help at stat.math.ethz.ch
> Subject: [R] global normalization
> Hello all,
> I have question about global normalization.
> I have data from big experement(two-color cDNA arrays) where 
> used three
> different layouts but the same set of genes. 
> I used limma package for within array normalization.
> My question is: how I can do between array normalization 
> (global) if arrays have
> different layout(different location and different number 
> technical replicates
> (number of spots of a gene on an array))?  
> Sincerely, Natalia.

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