[R] methods for interval-censored data

[A.J. Rossini]

>>>>> "EP" == Emmanuel Paradis <paradis at isem.univ-montp2.fr> writes:


    EP> Dear all, Are there functions or packages in R that can handle
    EP> interval-censored data? I have looked in various packages
    EP> (such as survival5 or event), but it seems that only
    EP> right-censored data can be analysed.

What do you want to do?  1-sample? regression models?  hypothesis
testing?  This isn't clear. 

Also, what assumptions are you referring to?  Continuous examination
process, or discrete examination process?  

There aren't clear choices for fitting -- for the semiparametric
regression models, the properties of the many approaches for variance
estimation for regression parameters aren't well understood.

For parameteric models, Jim gave the answer and has a paper detailing
the characteristics of the approaches (Jim - did you ever publish
this?) 

    EP> More generally, are there methods to analyse both
    EP> interval-censored observations and right-censored observations
    EP> in the same data set?

All right censored observations are inherently interval censored, take
the interval (C,\infty).

best,
-tony

-- 
A.J. Rossini				Rsrch. Asst. Prof. of Biostatistics
BlindGlobe Networks (home/default)	rossini at blindglobe.net	
UW Biostat/Center for AIDS Research	rossini at u.washington.edu	
FHCRC/SCHARP/HIV Vaccine Trials Net	rossini at scharp.org

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