[R] RE: dna library

Matthew Nelson MattN at esperion.com
Fri Mar 24 12:56:11 CET 2000


Thanks for making this library available.  As a trained human geneticist,
but a pharmaceutical scientist who spends most of my time working on
non-genetics projects using S-Plus/RWin/R (Linux), I've often thought that
it would be nice to stick with the same set of tools when I put my
geneticist/bioinformaticist hat back on.  In fact, I will often reformat
various genetics/DNA data sets for analysis in R.

Having said that, I would be happy to contribute to further development of
the library.  I will look for opportunities to use it and pass bug-reports
along to you.  I will also consider ways that it could be enhanced.  If
there are other ways that you feel I could contribute, please let me know.
I have five years of experience programming at various levels in S/R, and am
comfortable coding in C/C++.



Matthew R. Nelson, Ph.D.
Information Scientist
Esperion Therapeutics, Inc.
3621 S. State St.
695 KMS Place
Ann Arbor, MI 48108

Phone: (734) 332-0506 x235
Fax: (734) 332-0516
email: mnelson at esperion.com
web: http://www.esperion.com
-----Original Message-----
From: Jim Lindsey [mailto:jlindsey at alpha.luc.ac.be]
Sent: Thursday, March 23, 2000 12:44 PM
To: r-announce at stat.math.ethz.ch
Subject: dna library

I have just placed version 0.2 alpha of my library, dna, on my web
page at
The R functions in this library cover most of the basic methods of
dna and protein sequence analysis. The library includes ports of
CLUSTAL W for multiple sequence alignment and flip for finding open
reading frames in a dna sequence.
  There are an enormous number of interesting and challenging
statistical problems in current molecular biology and I am hoping that
making these procedures available to the R community will encourage
people to get involved.
  Some links to useful sites for learning about molecular biology can
be found at
  Comments and suggestions for further inclusions in the library are
very welcome.

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