Hello,

I am performing GO term enrichment analysis in my organism of interest (bos taurus) using the org.Bt.eg.db and GO.db package. However, since the GO.db package uses the "lite" version of the Gene Onthology database, all IEA (Inferred from Electronic Annotation) terms are absent. In cattle, this makes the annotation pretty barren (Over 60% of my genes have no GO annotation at all). Therefore, I am looking for ways to rebuild the GO.sqlite file used by GO.db using the full GO database. However I cannot find any indication on how to do so, either from the package source (where the file is already packaged) or from its manual. Could anyone point me in the right direction?

Thank you,
________________________________________________________
Eric Fournier, B. Sc.
Research Assistant in Bioinformatics
Université Laval, Qc, Canada
eric.fournier.4@ulaval.ca
418-656-2131 x 11465


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