Hi,

I would like to know if there is a way to specify Q75 be used for the locfunc in the estimateSizeFactors function of DESeq2 (instead of the default median).

Calling estimateSizeFactorsForMatrix with locfunc=quantile does return sizeFactors based on min, Q25, median, Q75 and max, and one can then go through the normalizationFactors steps to do so, but it would be handy to know how to do this directly in the estimateSizeFactors function, or even the DESeq call itself.

Thanks,
Dan Schnell

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