Hi, Dr. Smyth:
 
Thanks for the info. I used limma a lot but not much on voom.  I will give a shot on voom. Thanks again and best Ming
 
> Date: Thu, 30 Jan 2014 13:05:57 +1100
> From: smyth@wehi.EDU.AU
> To: yi02@hotmail.com
> CC: bioconductor@r-project.org
> Subject: limma-voom
> 
> Hi Ming,
> 
> voom is part of the limma package.  There is a voom case study in the 
> limma User's Guide with complete working code.  It is the last case study 
> in the users guide.
> 
> voom works fine with either counts, or fractional counts, or scaled 
> counts.
> 
> We are currently finalizing additional voom code to detect differential 
> splicing.  That code isn't in the public package, but will be soon.
> 
> Best wishes
> Gordon
> 
> On Thu, 30 Jan 2014, Ming Yi wrote:
> 
> > I found the following documents
> >
> > http://stuff.mit.edu/afs/athena/software/r/r_v2.15.1/lib/R/library/limma/html/voom.html
> > http://www.bioconductor.org/packages/release/bioc/vignettes/limma/inst/doc/usersguide.pdf
> > http://www.statsci.org/smyth/pubs/VoomPreprint.pdf
> >
> > But I could not find the real limma-voom package document. Is voom just 
> > as normalization function prior to using limma linear model? Any good 
> > examples of case study of working commands available as example?
> >
> > Thanks again!
> > Ming
> 
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