Thanks for the clarification Adrian. Could you please recommend some key
publications about GO terminology? I would like to understand this more in
depth.

Bernardo


2013/11/1 Adrian Alexa <adrian.alexa@gmail.com>

> Hi Bernardo,
>
> this is normal and it is a consequence of the True Path Rule. After all,
> you want to perform the enrichment test on the GO ontology not only on a
> selected number of GO terms.
>
> Regards,
> Adrian
>
>
>
>
> On Tue, Oct 29, 2013 at 7:20 PM, Bernardo Bello <popnard@gmail.com> wrote:
>
>> Possible answer -> These new GO terms seem to be the parents of the
>> already
>> GO terms present in my original dataset.
>>
>> Original question:
>>
>> Hi there,
>>
>> I ran an enrichment analysis with custom annotations using TopGO and
>> surprisingly I obtained new GO terms inside the significant GO terms.
>>
>> Is that  possible? The only reason I can imagine this is possible is
>> because TopGO adds new GO terms based on the input GO terms, since GO
>> ontology is structured hierarchically.
>>
>> Please let me know if you need more details about the experiment.
>>
>> Code:
>>
>>
>> https://drive.google.com/file/d/0B8-ZAuZe8jldbjNuTHhNeXRVX00/edit?usp=sharing
>>
>> TopGO output:
>>
>>
>> https://drive.google.com/file/d/0B8-ZAuZe8jldZnlYUzlxZ3psMWc/edit?usp=sharing
>>
>> Thanks, Bernardo
>>
>>
>> --
>>
>> *Bernardo Bello Ortí*
>>
>>
>> PhD student
>>
>> CReSA-IRTA
>>
>> Campus de Bellaterra-Universitat Autònoma de Barcelona
>>
>> Edifici CReSA
>>
>> 08193  Bellaterra (Barcelona, Spain)
>>
>> Tel.: 647 42 52 63 *www.cresa.es  *
>>
>> *
>> *
>>
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>>
>>
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>>
>
>


-- 

*Bernardo Bello Ortí*

PhD student

CReSA-IRTA

Campus de Bellaterra-Universitat Autònoma de Barcelona

Edifici CReSA

08193  Bellaterra (Barcelona, Spain)

Tel.: 647 42 52 63 *www.cresa.es  *

*
*

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