Possible answer -> These new GO terms seem to be the parents of the already
GO terms present in my original dataset.

Original question:

Hi there,

I ran an enrichment analysis with custom annotations using TopGO and
surprisingly I obtained new GO terms inside the significant GO terms.

Is that  possible? The only reason I can imagine this is possible is
because TopGO adds new GO terms based on the input GO terms, since GO
ontology is structured hierarchically.

Please let me know if you need more details about the experiment.

Code:

https://drive.google.com/file/d/0B8-ZAuZe8jldbjNuTHhNeXRVX00/edit?usp=sharing

TopGO output:

https://drive.google.com/file/d/0B8-ZAuZe8jldZnlYUzlxZ3psMWc/edit?usp=sharing

Thanks, Bernardo


-- 

*Bernardo Bello Ortí*

PhD student

CReSA-IRTA

Campus de Bellaterra-Universitat Auṭnoma de Barcelona

Edifici CReSA

08193  Bellaterra (Barcelona, Spain)

Tel.: 647 42 52 63 *www.cresa.es  *

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