On Wed, Aug 7, 2013 at 1:24 PM, Kevin Coombes <kevin.r.coombes@gmail.com>wrote:

> That's because you (and many other people) actually want to filter on the
> (posterior) probability that the log fold change is bigger than some
> (prespecified) value that you believe is biologically meaningful.


This isn't a posterior probability, but how about ranking using Limma's
TREAT method?

McCarthy, D. J., & Smyth, G. K. (2009). Testing significance relative to a
fold-change threshold is a TREAT. *Bioinformatics*, *25*(6), 765-771.

	[[alternative HTML version deleted]]

