Good point -- thank you for catching that.


On Mon, Nov 26, 2012 at 12:35 PM, Ryan C. Thompson <rct@thompsonclan.org>wrote:

> It doesn't seem that the Wald test is compensating for anything, since the
> authors show that putting their dispersion estimates into edgeR causes it
> to produce nearly identical results.
>
>
>
> On 11/26/2012 10:24 AM, Tim Triche, Jr. wrote:
>
>> The supplement mentioned by the authors in their final paragraph is also
>> attached (here).  It is worth at least a glance.  I wonder whether the
>> notoriously anticonservative Wald test is responsible for recovering
>> information lost to over-shrinkage.
>>
>


-- 
*A model is a lie that helps you see the truth.*
*
*
Howard Skipper<http://cancerres.aacrjournals.org/content/31/9/1173.full.pdf>

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