On Sat, Aug 25, 2012 at 4:31 PM, wang peter <wng.peter@gmail.com> wrote:

> it also generate another problem
>
> if i use one factor, as you suggested :  control_0h, control_0h, ...,
> treated_0h, ..., treated_48h, etc.
>
> design = model.matrix( ~ fac)
> contmat = makeContrasts(treated_6h-control_6h,treated_12h-control_12h)
>
> will the glm use all the samples to do regression for single comparision?
>
> I believe it will "do the right thing", yes.

Sean


> i hope glm use all to do regression, even on single test
> like:treated_6h-control_6h
>
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