Hi all,

I'm trying to analyze Illumina array of gene expression. The file format is .idat which is encrypted data.

I downloaded IDATreader packages as Mike suggested in some of previous post. I also install openssl for my mac os x. http://www.compbio.group.cam.ac.uk/software/idatreader

But when I tried to read idat file error message is prompted.

source("/Library/R/readIDAT.R")
filenames<-dir(patter="idat")
idat<-readIDAT(file=filenames[1])

> idat<-readIDAT(file=filenames[1])
Decrypting to XML
Error in .C("decryptSSL", as.character(file), as.character(tempFile),  :
  C symbol name "decryptSSL" not in DLL for package "IDATreader"

> sessionInfo()
R version 2.15.0 (2012-03-30)
Platform: i386-apple-darwin9.8.0/i386 (32-bit)

locale:
[1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base

other attached packages:
[1] BiocInstaller_1.4.7

loaded via a namespace (and not attached):
[1] tools_2.15.0

Please let me have any advices to solve this problem.

Seungyeul Yoo

Postdoctoral Fellow
Jun Zhu's Laboratory
Institute of Genomics and Multiscale Biology
Department of Genetics and Genomic Sciences
Mount Sinai School of Medicine





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