Dear List
 I'm dealing with a very unbalanced experiment(affymetrix gene 1.0st) with
14 experiments in one biological condition and only 3 experiments in the
other condition.
The big variance is observed in the most populated condition...so in your
opinion what kind of test could be more useful to retrieve a list of
differentially expressed genes between the 2 conditions?
At the moment i'm using anova but i have several doubts concerning the
fixed effect assumed for each gene . This could be overcome using
manova....or It better that i use some non parametric tests like sam o
wilcoxon?

thank you for any tips
Best
Guido

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