Hello,

I am trying to validate few LOH regions using SNP genotype data. I am
assuming that if it is a LOH, it will contain predominantly homozygous
genotypes. For simplicity, I chose 15 SNPs per ~70 kb LOH region.

Now I need to calculate the heterozygosity for LOHs in each samples using
genotype data of 15 SNPs.

Does anyone know the way to calculate the heterozygous % per sample using a
set of SNP genotype data?

Your help will be greatly appreciated.

--Yadav

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