I am thinking of using GOseq to obtain enriched GO terms for RNA-Seq clustering results. I plan to transform the RNA-Seq data before running clustering to make it homoskedastic.  When running GOseq, I would provide the list of genes that cluster together as the list of "DE genes".

Question: Is this an appropriate usage of GOseq?  Or can/should I just use a standard Fisher's Exact Test?

Thanks,
Julie

Julie Leonard
Computational Biologist
Syngenta Biotechnology Inc.
(919) 281-7449
julie.leonard@syngenta.com




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