Dear Sir or Madam,

I am interested in using Bioconductor to analyze and compare some data I’ve recently acquired and was wondering if you could help direct me to an appropriate analysis package.

I have two sets of data, from two separate groups of AML patients.  One set is of 96 patients, the other set is of 178 patients, and I have sequencing data for both groups.  For a few genes of interest the first group’s dataset, it looked like there were a number of SNPs that were found with a higher than normal frequency among the 96 patients. What I would like to do is find out if the frequency of these SNPs is the same in the dataset of 178 patients.  I just need a way of analyzing the frequency of SNPs in a large set of sequences.

Thanks very much,
Jung



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