Research Associate - Biostatistics/Bioinformatics 

Department of Plant Sciences, University of Cambridge, UK

 

Modelling control of meiotic recombination frequency

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Meiotic recombination generates novel combinations of genetic variation via
reciprocal exchange between homologous chromosomes. To better understand
this process we are generating genome-wide recombination frequency maps in
the model plant Arabidopsis thaliana. 



The research associate will integrate recombination frequency maps with
genomic, epigenomic and population genetic data. They will then develop a
quantitative model for control of recombination frequency, which will be
tested using experimental genetics. This research has important implications
for population genetics and food security via crop breeding. 



The research associate will work jointly within Dr Ian Henderson's
experimental research group and the Departmental Bioinformatics Group led by
Dr Krys Kelly. The bioinformatics group currently consists of five people
developing statistical methodology and analysing genome-wide patterns of
small RNAs and epigenetic information in association with Prof Sir David
Baulcombe. 



Applicants should have a Ph.D and substantial experience of a statistical
language (e.g. R, Matlab). Experience in statistics, statistical genetics,
quantitative genetics or genomics would also be beneficial. 



Vacancy Reference No: PD09942. Salary: Ł27,319-Ł35,646 pa. 

The post is available for 2 years, in the first instance.



Download the further particulars and details of how to apply from
http://www.plantsci.cam.ac.uk/jobs/index.html

Closing date is 12 noon on 16 December 2011.




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