you can read about formally calibrated outlier assessment for microarrays in

http://bioinformatics.oxfordjournals.org/content/25/1/48

On Wed, Nov 2, 2011 at 10:04 AM, Richard Friedman <
friedman@cancercenter.columbia.edu> wrote:

> Dear Bioconductor List,
>
>        Does anyone know of an objective criterion for the identification
> of outlying arrays
> by pca?
>
>        I usually do this subjectively. However the experimental
> investigator whom I am helping
> has a different subjective sense than I do, so that I wonder if there is a
> hard-and-fast criterion.
>
> Thanks and best wishes,
> Rich
> ------------------------------**------------------------------
> Richard A. Friedman, PhD
> Associate Research Scientist,
> Biomedical Informatics Shared Resource
> Herbert Irving Comprehensive Cancer Center (HICCC)
> Lecturer,
> Department of Biomedical Informatics (DBMI)
> Educational Coordinator,
> Center for Computational Biology and Bioinformatics (C2B2)/
> National Center for Multiscale Analysis of Genomic Networks (MAGNet)
> Room 824
> Irving Cancer Research Center
> Columbia University
> 1130 St. Nicholas Ave
> New York, NY 10032
> (212)851-4765 (voice)
> friedman@cancercenter.**columbia.edu <friedman@cancercenter.columbia.edu>
> http://cancercenter.columbia.**edu/~friedman/<http://cancercenter.columbia.edu/%7Efriedman/>
>
> I am a Bayesian. When I see a multiple-choice question on a test and I
> don't
> know the answer I say "eeney-meaney-miney-moe".
>
> Rose Friedman, Age 14
>
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