Dear List,

I have been thinking with using limma package to perform some time series 
analysis. There is a simple example in limma's manual. However, it seems that 
the analysis in the manual does not consider the repeated measurement effect for 
time series data.
I am wondering if limma has developed any method to deal with such time series 
data. Or I have to manually add random effects term in the model. But I really 
don't know how to do this. Could some one or Gordon clarify on this topic?
My apology first, if this topic has been intensively discussed.
Thank you.

Xiaokuan
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