Hi All,

I am new to R and trying to extract  data from GEO database. It seems everything is fine with IMAC (desktop) when I practice the package GEOquery. However, there are problems when I try to use my PC labtop.

I copy and paste one of  my problems below:

>gse2553 <- getGEO("GSE2553", GSEMatrix = TRUE)
Found 1 file(s)
GSE2553_series_matrix.txt.gz
Error in file(con, "r") : cannot open the connection
In addition: Warning messages:
1: In download.file(sprintf("ftp://ftp.ncbi.nih.gov/pub/geo/DATA/SeriesMatrix/%s/%s",  :
  download had nonzero exit status
2: In file(con, "r") :
  cannot open file 'C:\DOCUME~1\huangji\LOCALS~1\Temp\RtmpmPEm8S/GSE2553_series_matrix.txt.gz': No such file or directory
>

Can somebody help me ?

Many thanks

Jing

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