Hi,
I got an below error message while running the edgeR.

> d10 <- estimateTagwiseDisp(d10, prior.n = 10, grid.length = 500)
Using grid search to estimate tagwise dispersion.
> prior.n10 <- estimateSmoothing(d10)
Warning message:
In .odls(scores.g = scores, info.g = exp.inf) :
  Estimate of overdispersion of likelihood scores is strictly zero.
 Returning min val close to zero (1e-08).

I was not sure, what does this mean? Can anyone help me to troubleshoot
this?
I would great appreciate it.

Thanks,
Sridhara

-- 
Sridhara G Kunjeti
PhD Candidate
University of Delaware
Department of Plant and Soil Science
email- sridhara@udel.edu
Ph: 832-566-0011

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