Hi all,

I am comparing a number of cell types, and am wanting to find the signature
genes of each cell type. I used the limma package to do this. The signature
genes of a given cell type are found by the fold different between the given
cell type and grand mean of all the cell types, as well as the BH-adjusted
p-values. I want to add another condition to test the consistency of
expression levels of the selected genes for each cell type. I can do this by
looking at the standard deviations of gene expressions between replicates. I
am just wondering if there is any function in limma or other BioConductor
package to do this.

Thank you in advance,

Wendy

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