Hi bioconductor mailing list,
I have severall datasets and all of which share 2 reference samples. I want
to do a normalization that takes this into account, so that each dataset is
normalized against its own reference. In the end I would like to have all
datasets normalized in this way, so that when thrown into a PCA the
reference samples cluster together.

Your help is greatly appreciated! If possible, please guide me to
BioC-packages or functions as I am pretty new to BioC.

Thanks in advance, Andreas

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