RESEARCH ASSOCIATE - BIOSTATISTICS/BIOINFORMATICS

 

Department of Plant Sciences, University of Cambridge

 

Salary: Ł27,319-Ł35,646 pa

Limit of Tenure applies*

 

Genome-wide mapping and biostatistical analysis of meiotic recombination 

 

Meiotic recombination generates novel combinations of genetic variation via
reciprocal exchange between homologous chromosomes. To better understand
this process we are generating genome-wide recombination frequency maps in
the model plant Arabidopsis thaliana. This research has important
implications for population genetics and food security. 

 

The Research Associate will analyse high-throughput sequencing genotype data
(Illumina) to generate recombination frequency maps. They will then model
recombination frequency in terms of genomic (transcription, natural
variation, small RNAs) and epigenomic (cytosine methylation, histone
methylation, histone variants) features using publicly available whole
genome datasets. 

 

The Research Associate will work jointly within Dr Ian Henderson's
experimental research group and the Departmental Bioinformatics Group led by
Dr Krys Kelly. The bioinformatics group currently consists of 6 people
developing statistical methodology and analysing genome-wide patterns of
small RNAs and epigenetic information in association with Prof Sir David
Baulcombe. 

 

Applicants should have a Ph.D and substantial experience of a statistical
language (e.g. R, Matlab). Experience in statistics, statistical genetics,
quantitative genetics or genomics would also be beneficial. 

 

For further particulars please visit the Department website at
http://www.plantsci.cam.ac.uk/jobs/index.html or contact Dr Ian Henderson
(email: irh25@cam.ac.uk) 

 

To apply, please send a covering letter, CV, a Chris/6 cover sheet (parts I
and III only) - http://www.admin.cam.ac.uk/offices/hr/forms/chris6/ - and
the names and contact details (including email addresses) of 3 referees to
Ombretta Orsini, Head of Department's Secretary, Department of Plant
Sciences, Downing Street, Cambridge, CB2 3EA or email: oo203@cam.ac.uk 

 

* Limit of tenure: The post is available for 2 years, in the first instance.

 

Quote Reference: PD07707,Closing Date: 23 February 2011

 


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