Unfortunately, we have become aware recently that the FC calculation in Limma
Is not correct.  We input the expression values as log2 transformed values.  The
Average log expression value is then calculated by averaging the log values (ave(logX)).
However, this is NOT the log of the average expression value (logXbar) and so the reported
FC is therefore not correct.
Is there a possibility that the code can be corrected?

Lana Schaffer
Biostatistics, Informatics
DNA Array Core Facility
858-784-2263


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