
Hi there,
I am trying to use LIMMA to analyze gene expression data from an experiment which has dose response but only one replicate at each dose. I tried to fit a linear model using lmfit(). I used the doses as continuous variable. I do the ebayes fit and finally do decide tests with adj p values (BH corrected). I get coefficients, intercept and dose as output with t-stat and p values for each. I was wondering how to interpret these. What does intercept, dose and coefficients mean in this case? The data matrix I read into R was Affy Plus2 chip data for 4 doses of a compound. Any help would be greatly appreciated.
Best Regards,Som. 		 	   		  
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