
You can use the metal program available at the broad website with what
you have. If you have the standard error you can try the inverse
varience option
The bioconductor geneMeta program has REM specifically : uses the
t-statistic which I think you can get if you have the standand error and
the OR. It would require  minor modification of some function however.
The number of observations in each group is the number of SNPs no?
Cheers
Paul







-----Original Message-----
From: Laura Rodriguez Murillo <laura.lmurillo@gmail.com>
To: bioconductor@stat.math.ethz.ch
Subject: [BioC] meta-analysis with P values
Date: Wed, 14 Jul 2010 15:55:26 -0400


Hi dear list,

My question is on meta-analysis. I have three studies on the association of
a SNP with a disease and I need to do a random-effects meta-analysis with my
data. I only have the individual P value, the odds ratio and sample size
from each study. I've checked rmeta and meta packages but it seems to me
that I need to know the number of observations on each group, which I don't
have in this case. Is there any other package I can use that accepts doing
meta-analysis with these data?

Thanks a lot for your help!

Laura

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