Respected Sir/Madam,

I am a jr research fellow of Calcutta University, India working on Systems Biology. I have found GEO soft files in the GEO database. I want to know whether the data are already normalized or not. If those are not normalized is it possible to normalize those using Bioconductor? I am providing a part of one of the soft file to make my problem clear : 



 

 

 

  ID_REF

  GSM159172

  GSM159173

  GSM159271

  GSM159272

 

 

  AFFX-BioB-3_at

  88.00277

  76.18801

  74.70855

  78.48763

 

 

  AFFX-BioB-5_at

  64.32276

  57.14953

  56.92367

  58.82795

 

 

  AFFX-BioB-M_at

  89.22734

  89.86254

  88.61163

  82.42649

 

 

  AFFX-BioC-3_at

  298.9344

  246.6433

  303.7554

  248.4071

 


Thanking you,
yours faithfully,
Chittabrata Mal
JRF, Calcutta university,
Kolkata, India
 
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