Hi,

I have a question about the annotation package GO. Currently I am trying to
use the package GOSim (developed by Holger Fröhlich), which requires the GO
package. My organism of interest is a bacterial species Streptomyces
coelicolor. The GO annotations for this antibiotics-producing organism are
available from Sanger center website
(http://streptomyces.org.uk/GO/index.html). However, I don't think these
annotations are part of the GO database/package. The Entrez geneIDs for this
organism are not linked to their GO annotations. More importantly (for me),
GOSim has the information content of each GO term based on the number of
genes that have been annotated with that particular GO term. Hence,
modifying the gene/GO database can change the information content of the GO
terms. Is it possible to add the GO annotations of this microorganism to the
GO package? (Perhaps in a new release in the future?)

 

Thanks,

Salim

 

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Salim Charaniya

PhD candidate

Department of Chemical Engineering and Materials Science

University of Minnesota, Minneapolis

Email: salim@cems.umn.edu

Phone: (612) 625-3051

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