Hi all,
I have received time series dataset which I could not control the
experimental design.

And here it is. This is a 2 conditions time series (placebo/treatment) with
5 time points.
The main issue I encounter is that the number of replicates at each time
point is not the same:
time ttt placebo
t0 2 7
t3 3 6
t7 3 6
t14 2 5
t28 5 4

I tried to use the timecourse package but obviously I can't set the required
replicate matrix.
Unless I remove some samples (more or less justified by their poor quality)
so that the number of sample becomes constant, does anyone could give me
some good advice ?

In advance many thanks

Greg

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