Hi all

 

I am working with biological replicates and I am a bit worried about the
biological variation between samples.

For example, the abundance of a certain gene in sample 1 could be
hundreds of time higher or lower than in sample B. If this is the case, 

this will significantly affect the P-value in the t-test. 

 

As such, my question is whether there is a way we can account for this
fact in the statistical analysis?

 

I will be much grateful if you guys could shed some light on this topic?


 

Thank you

Yogi

 

 



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