Dear all,

Currently I am using SAM to identify the differentially expressed genes
between two groups. The first group has 99 experiments, and the second one
has around 15 experiments. When I use the SAM to do the analysis, I identify
so many differentially expressed genes even if I set the FDR threshold to be
very low. I am just wondering if I should just randomly pick 15 experiments
from the first group, and to compare the 15 experiments on the second group
?  or does it matter ?

I greatly appreciate for any comment or advice.


Thanks,




-- 
Lam C. Tsoi (Alex)
Medical University of South Carolina

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