Dear all,
 
I was wondering if there are other methods for combining replicate spots other than the average or the median.
I am asking this in concern with CGH data analysis because I do not know how, and if, we can take advantage of the genomic structure of the array CGH data for combining replicate spots.
 
For the sake of the argument I put below two hypothetical examples:
- Combining replicate spots in a different way depending on what region of the chromosome or genome they are;
- Or give more weight to spots that we know that have more reliability. 
 
Something like this if you know what I mean.


Best regards

João Fadista
Ph.d. student


 	
 	 Danish Institute of Agricultural Sciences	
Research Centre Foulum	
Dept. of Genetics and Biotechnology	
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DK-8830 Tjele	
 	
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