Good evening.

This question is maybe off-topic. I am sorry for this spam for most of you.

I am studying the periodicity of DNA sequence. The approach I take is to
investigate the frequency of specific motif and distance between two
succesive occurrence of the motif. To acquire the frequency relative to
random sequence, I need to generate a random sequence with the same
composition of bases as original sequence. I am looking for the public
software to help me in calculating the relative frequency of getting random
sequences. I look forward to any of comments or  advice on this problem.
Thank you very much.

Best regards,

Joo Sang Lee
Department of Physics,
Northwestern University

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