[BioC] ComBat() -- run with one sample in one batch
Guest [guest]
guest at bioconductor.org
Fri Jun 6 20:43:49 CEST 2014
Hi,
Is there a work around for ComBat() where I can run the function if I have only one sample in one batch?
I'm working with affymetrix, human chip U133A and trying to remove batch effect on scan date. I have some samples that were scanned individually on separate dates. So there are some dates where only one sample was run.
Any insight regarding this will be appreciated.
Thanks!
-- output of sessionInfo():
> sessionInfo()
R version 3.1.0 (2014-04-10)
Platform: x86_64-apple-darwin13.1.0 (64-bit)
locale:
[1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8
attached base packages:
[1] parallel stats graphics grDevices utils datasets methods base
other attached packages:
[1] bladderbatch_1.2.0 sva_3.10.0 mgcv_1.7-29 nlme_3.1-117 corpcor_1.6.6 affy_1.42.2
[7] Biobase_2.24.0 BiocGenerics_0.10.0 BiocInstaller_1.14.2
loaded via a namespace (and not attached):
[1] affyio_1.32.0 grid_3.1.0 lattice_0.20-29 Matrix_1.1-3 preprocessCore_1.26.1
[6] tools_3.1.0 zlibbioc_1.10.0
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