[BioC] Tool inqured to analysis array expression and cell line screening data

Ran [guest] guest at bioconductor.org
Mon Jan 27 06:01:38 CET 2014

I would like your suggestion for the bioinformatics approaches how to select biomarker genes in the cancer cell lines. We have IC50 data for a compounds screening to about 100 cell line, resulted in compound sensitive or resistant for the cell lines. We would like to have tool to select gene or marker correlated with the gene expression or copy number changes. How can we use the public data (e.g. CCLE’s gene expression etc.) to select the genes or biomarkers – which correlate with the IC50 screening for the cell line?  Thank you.

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