[BioC] Cluster stability/robustness

Wolfgang Huber whuber at embl.de
Sat Jan 18 01:01:21 CET 2014


Rafi

I’ve found the ‘clue’ package on CRAN very useful for similar questions.
http://cran.r-project.org/web/packages/clue/index.html

	Best wishes
		Wolfgang

Il giorno 16 Jan 2014, alle ore 17:03, Rafi [guest] <guest at bioconductor.org> ha scritto:

> 
> Hello,
> 
> I have used hclust to cluster a large data of 10K genes and 800 conditions and got 150 clusters as output.  
> 
> How can I show that these clusters are stable? 
> 
> What are the common metrics or parameters that are used to show that we have got a stable/robust cluster?
> 
> Is there any package that will do this? 
> 
> Your reply will be very helpful. Thank you for your time in advance.
> 
> Thanks
> Rafi
> 
> -- output of sessionInfo(): 
> 
> R version 3.0.2 (2013-09-25)
> Platform: x86_64-w64-mingw32/x64 (64-bit)
> 
> locale:
> [1] LC_COLLATE=English_United States.1252  LC_CTYPE=English_United States.1252    LC_MONETARY=English_United States.1252
> [4] LC_NUMERIC=C                           LC_TIME=English_United States.1252    
> 
> attached base packages:
> [1] stats     graphics  grDevices utils     datasets  methods   base     
> 
> loaded via a namespace (and not attached):
> [1] tools_3.0.2
> 
> --
> Sent via the guest posting facility at bioconductor.org.
> 
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