[BioC] RNA seq

[Minni [guest]]

I am a beginner of R studio. I downloaded the annotation data by using this command:
>annoation(gse), >platf<-getGEO(annotation(gse),AnnotGPL=TRUE), which I got stuck for the next step. My main goal is to get the differential genes from GSE12946 (RNA-seq). Please guide me through it. Thanks 

 -- output of sessionInfo(): 

annotation(gse)
[1] "GPL9052"

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