[BioC] Error in sort(abs(diff(genomdat)))[1:n.keep]
Conan [guest]
guest at bioconductor.org
Fri May 24 16:04:59 CEST 2013
Hi all, I'm using a package ExomeCNV to call LOH and got an error in step "Combine multiple positions into LOH segments"
the.loh = multi.LOH.analyze(normal, tumor, all.loh.ls=list(eLOH), test.alpha=0.001, method="variance.f", sdundo=c(0,0), alpha=c(0.5,0.1))
Analyzing: Sample.1
Error in sort(abs(diff(genomdat)))[1:n.keep] :
only 0's may be mixed with negative subscripts
In addition: Warning message:
In CNA(data$baf, strip.chr.name(data$chr), data$position, data.type = "binary") :
markers with missing chrom and/or maploc removed
ExomeCNV actually implement package DNAcopy in this step, and I can't tell how to bypass this problem since the "n.keep" isn't from ExomeCNV's code. I would really appreciate your expertise, thank you.
-- output of sessionInfo():
R version 3.0.1 (2013-05-16)
Platform: x86_64-w64-mingw32/x64 (64-bit)
locale:
[1] LC_COLLATE=English_United States.1252 LC_CTYPE=English_United States.1252 LC_MONETARY=English_United States.1252 LC_NUMERIC=C
[5] LC_TIME=English_United States.1252
attached base packages:
[1] stats graphics grDevices utils datasets methods base
other attached packages:
[1] ExomeCNV_1.4 DNAcopy_1.34.0 BiocInstaller_1.10.1
loaded via a namespace (and not attached):
[1] tools_3.0.1
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