[BioC] How to pool subgroups for makeContrasts() and subsequent limma analysis?
René
rene.boettcher86 at googlemail.com
Tue Feb 19 14:33:58 CET 2013
Dear all,
As I am still stuck on this topic, I would like to ask whether it is OK to
completely replace the comparison (B1+B2+B3)/3 - A by a separate run of B-A in
order to obtain some meaningful results. By heart I would say that this is not
the case, as it would mean combining two independent design matrices and
therefore two different models. Nevertheless, I am running out of ideas on how
to perform this analysis and I would like to finish it by the end of February.
Any recommendations are more than welcome.
Best regards
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