[BioC] enrichment packages that accept t-stat (or related stat) as input

[Hooiveld, Guido]

Hi,
Regarding GSEA; do you know about the so-called 'pre-ranked' analysis that will do exactly what you describe?
http://www.broadinstitute.org/gsea/doc/GSEAUserGuideFrame.html?GSEA_Preranked_Page

Guido

-----Original Message-----
From: bioconductor-bounces at r-project.org [mailto:bioconductor-bounces at r-project.org] On Behalf Of Juliet Hannah
Sent: Wednesday, August 28, 2013 20:05
To: Bioconductor mailing list
Subject: [BioC] enrichment packages that accept t-stat (or related stat) as input

All,

I am looking for an Bioconductor enrichment package that does something similar to GSEA for pre-computed test statistics. This method would not rely on a cutoff. That is, rather than passing an expression matrix, one can compute summarizes outside of the package (such as a limma t), and then pass these. Any suggestions?

Thanks,

Juliet

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